These examples show how the Nawderian theorem and the TriadicFrameworks stack apply to medical systems: drug half-life, cardiac rhythm, dose-response curves, and physiological resonance.
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Core TriadicFrameworks mathematical objects used:
tโ/โ = ln(2) / (ฮฮ)
If \( ฮ \) decreases by 10%, how does the half-life change?
R = T_f Dโ
If \( T_f \) increases by 8%, what is the percent change in R?
S = X / (1 + e^{-ฯ_r})
If \( ฯ_r \) increases, how does S change qualitatively?
\( t_{1/2}' = t_{1/2} / 0.9 \). Half-life increases by 11.1%.
Rhythm increases by 8%.
As \( ฯ_r \) increases, the exponential term shrinks โ S increases.
C = T_f / (Dโ + ฯ_r)
Describe how increasing ฯ_r and T_f affect clearance.
ฮ_f = Dโ - X โฯ_r
Describe how quadrupling ฯ_r affects ฮ_f.
I = X ln(1 + Dโ ฯ_r)
Describe how increasing ฯ_r affects I.
S_sat = (ฮฮ + T_f) / (1 + e^{-Dโ ฯ_r})
Analyze effects of increasing ฯ_r and ฮฮ.
F = Fโ ฯ_rยฒ / (Dโ + ฮฮ)
Describe how changes in ฯ_r and ฮฮ affect flow.
ฮ + ฮ โ ฮฮ โ ln(2)/ฮฮ โ tโ/โ
T_f ร Dโ โ R
ฯ_r โ e^{-ฯ_r} โ 1 + e^{-ฯ_r} โ X รท (...) โ S